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The discovery of quinoline derivatives, as NF-κB inducing kinase (NIK) inhibitors with anti-inflammatory effects in vitro, low toxicities against T cell growth - ScienceDirect
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Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A
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Transcreener ADP Assay Enables Evaluation of NIK Inhibitors in Lupus Drug Discovery - BellBrook Labs
Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K) | Journal of Medicinal Chemistry
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FEP+ calculations predict a stereochemical SAR switch for first-in-class indoline NIK inhibitors for multiple myeloma | Future Drug Discovery
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NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus | Nature Communications
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NIK compounds* inhibit NFkB activation mediated by Smac-mimetic in MM... | Download Scientific Diagram
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Transcreener ADP Assay Enables Evaluation of NIK Inhibitors in Lupus Drug Discovery - BellBrook Labs
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Effect of NIK inhibitors on NF-kB activity in MM cells with different... | Download Scientific Diagram
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Structure of the Nuclear Factor κB-inducing Kinase (NIK) Kinase Domain Reveals a Constitutively Active Conformation - Journal of Biological Chemistry
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Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A
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TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation - Shiode - - Hepatology - Wiley Online Library
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GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-κB-Dependent Mechanism - ScienceDirect
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